Tolerability
- Memantine displays a favorable tolerability profile even in long-term therapy.
- In studies of memantine, doctors assessed tolerability as good or very good in the vast majority of patients.
- In clinical studies the overall frequency of side effects was similar to placebo (EU SmPC), reported side effects do not exceed 2%.
- Memantine's metabolism is not influenced by the cytochrome P-450 system. Therefore memantine has a low potential for interactions in these multimorbid patients.
